White matter loss and oligodendrocyte dysfunction in HIV: a consequence of the infection, the antiretroviral therapy or both?

While the severe cognitive effects of HIV-associated dementia have been reduced by combined antiretroviral therapy (cART), nearly half of HIV-positive (HIV+) patients still suffer from some form of HIV-Associated Neurocognitive Disorders (HAND). While frank neuronal loss has been dramatically reduce...

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Veröffentlicht in:Brain Res
Hauptverfasser: Jensen, Brigid K., Roth, Lindsay M., Grinspan, Judith B., Jordan-Sciutto, Kelly L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779527/
https://ncbi.nlm.nih.gov/pubmed/31442414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146397
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