Suboptimal RNA–RNA interaction limits U1 snRNP inhibition of canonical mRNA 3’ processing

It is increasingly appreciated that U1 snRNP transcriptomically suppresses the usage of intronic polyadenylation site (PAS) of mRNAs, an outstanding question is why frequently used PASs are not suppressed. Here we found that U1 snRNP could be transiently associated with sequences upstream of actiona...

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Bibliographic Details
Published in:RNA Biol
Main Authors: Shi, Junjie, Deng, Yanhui, Huang, Shanshan, Huang, Chunliu, Wang, Jinkai, Xiang, Andy Peng, Yao, Chengguo
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779394/
https://ncbi.nlm.nih.gov/pubmed/31242075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1636596
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