Suboptimal RNA–RNA interaction limits U1 snRNP inhibition of canonical mRNA 3’ processing

It is increasingly appreciated that U1 snRNP transcriptomically suppresses the usage of intronic polyadenylation site (PAS) of mRNAs, an outstanding question is why frequently used PASs are not suppressed. Here we found that U1 snRNP could be transiently associated with sequences upstream of actiona...

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Publicat a:RNA Biol
Autors principals: Shi, Junjie, Deng, Yanhui, Huang, Shanshan, Huang, Chunliu, Wang, Jinkai, Xiang, Andy Peng, Yao, Chengguo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779394/
https://ncbi.nlm.nih.gov/pubmed/31242075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1636596
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