Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium

BACKGROUND: A glycocalyx envelope consisting of proteoglycans and adhering proteins covers endothelial cells, both the luminal and abluminal surface. We previously demonstrated that short-term loss of integrity of the luminal glycocalyx layer resulted in perturbed glomerular filtration barrier funct...

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Udgivet i:J Am Soc Nephrol
Main Authors: van den Berg, Bernard M., Wang, Gangqi, Boels, Margien G. S., Avramut, M. Cristina, Jansen, Erik, Sol, Wendy M. P. J., Lebrin, Franck, Jan van Zonneveld, Anton, de Koning, Eelco J. P., Vink, Hans, Gröne, Hermann-Josef, Carmeliet, Peter, van der Vlag, Johan, Rabelink, Ton J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2019
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779367/
https://ncbi.nlm.nih.gov/pubmed/31308073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019020192
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