Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium

BACKGROUND: A glycocalyx envelope consisting of proteoglycans and adhering proteins covers endothelial cells, both the luminal and abluminal surface. We previously demonstrated that short-term loss of integrity of the luminal glycocalyx layer resulted in perturbed glomerular filtration barrier funct...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: van den Berg, Bernard M., Wang, Gangqi, Boels, Margien G. S., Avramut, M. Cristina, Jansen, Erik, Sol, Wendy M. P. J., Lebrin, Franck, Jan van Zonneveld, Anton, de Koning, Eelco J. P., Vink, Hans, Gröne, Hermann-Josef, Carmeliet, Peter, van der Vlag, Johan, Rabelink, Ton J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779367/
https://ncbi.nlm.nih.gov/pubmed/31308073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019020192
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