Tissue-Resident Macrophages Promote Renal Cystic Disease

BACKGROUND: Mutations affecting cilia proteins have an established role in renal cyst formation. In mice, the rate of cystogenesis is influenced by the age at which cilia dysfunction occurs and whether the kidney has been injured. Disruption of cilia function before postnatal day 12–14 results in ra...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Zimmerman, Kurt A., Song, Cheng J., Li, Zhang, Lever, Jeremie M., Crossman, David K., Rains, Addison, Aloria, Ernald J., Gonzalez, Nancy M., Bassler, John R., Zhou, Juling, Crowley, Michael R., Revell, Dustin Z., Yan, Zhaoqi, Shan, Dan, Benveniste, Etty N., George, James F., Mrug, Michal, Yoder, Bradley K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2019
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779366/
https://ncbi.nlm.nih.gov/pubmed/31337691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018080810
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