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Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement
AKI accelerates cystogenesis. Because cystogenic mutations induce strong transcriptional responses similar to those seen after AKI, these responses may accelerate the progression of cystic renal disease. Here, we modulated the severity of the AKI-like response in Cys1(cpk/cpk) mice, a model that mim...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380643/ https://ncbi.nlm.nih.gov/pubmed/22518005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050442 |
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