Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement

AKI accelerates cystogenesis. Because cystogenic mutations induce strong transcriptional responses similar to those seen after AKI, these responses may accelerate the progression of cystic renal disease. Here, we modulated the severity of the AKI-like response in Cys1(cpk/cpk) mice, a model that mim...

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Autori principali: Zhou, Juling, Ouyang, Xiaosen, Schoeb, Trenton R., Bolisetty, Subhashini, Cui, Xiangqin, Mrug, Sylvie, Yoder, Bradley K., Johnson, Martin R., Szalai, Alexander J., Mrug, Michal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2012
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380643/
https://ncbi.nlm.nih.gov/pubmed/22518005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050442
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