Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement

AKI accelerates cystogenesis. Because cystogenic mutations induce strong transcriptional responses similar to those seen after AKI, these responses may accelerate the progression of cystic renal disease. Here, we modulated the severity of the AKI-like response in Cys1(cpk/cpk) mice, a model that mim...

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Hlavní autoři: Zhou, Juling, Ouyang, Xiaosen, Schoeb, Trenton R., Bolisetty, Subhashini, Cui, Xiangqin, Mrug, Sylvie, Yoder, Bradley K., Johnson, Martin R., Szalai, Alexander J., Mrug, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2012
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380643/
https://ncbi.nlm.nih.gov/pubmed/22518005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050442
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