Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice

Middle East respiratory syndrome-coronavirus (MERS-CoV) is an emerging virus that causes severe disease with fatal outcomes; however, there are currently no approved vaccines or specific treatments against MERS-CoV. Here, we developed a novel bivalent vaccine against MERS-CoV and rabies virus (RV) u...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Kato, Hirofumi, Takayama-Ito, Mutsuyo, Iizuka-Shiota, Itoe, Fukushi, Shuetsu, Posadas-Herrera, Guillermo, Horiya, Madoka, Satoh, Masaaki, Yoshikawa, Tomoki, Yamada, Souichi, Harada, Shizuko, Fujii, Hikaru, Shibamura, Miho, Inagaki, Takuya, Morimoto, Kinjiro, Saijo, Masayuki, Lim, Chang-Kweng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779238/
https://ncbi.nlm.nih.gov/pubmed/31589656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223684
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