Natural Resistance of Leishmania infantum to Miltefosine Contributes to the Low Efficacy in the Treatment of Visceral Leishmaniasis in Brazil

In India, visceral leishmaniasis (VL) caused by Leishmania donovani has been successfully treated with miltefosine with a cure rate of > 90%. To assess the efficacy and safety of oral miltefosine against Brazilian VL, which is caused by Leishmania infantum, a phase II, open-label, dose-escalation...

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Pubblicato in:Am J Trop Med Hyg
Autori principali: Carnielli, Juliana B. T., Monti-Rocha, Renata, Costa, Dorcas Lamounier, Molina Sesana, Aretha, Pansini, Laura N. N., Segatto, Marcela, Mottram, Jeremy C., Costa, Carlos Henrique Nery, Carvalho, Sílvio F. G., Dietze, Reynaldo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Tropical Medicine and Hygiene 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779219/
https://ncbi.nlm.nih.gov/pubmed/31436148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.18-0949
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