A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

BACKGROUND: Miltefosine has been used successfully to treat visceral leishmaniasis (VL) in India, but it was unsuccessful for VL in a clinical trial in Brazil. METHODS: To identify molecular markers that predict VL treatment failure whole genome sequencing of 26 L. infantum isolates, from cured and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EBioMedicine
Egile Nagusiak: Carnielli, Juliana B.T., Crouch, Kathryn, Forrester, Sarah, Silva, Vladimir Costa, Carvalho, Sílvio F.G., Damasceno, Jeziel D., Brown, Elaine, Dickens, Nicholas J., Costa, Dorcas L., Costa, Carlos H.N., Dietze, Reynaldo, Jeffares, Daniel C., Mottram, Jeremy C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Research paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197651/
https://ncbi.nlm.nih.gov/pubmed/30268832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.029
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