Involvement of Na/K-ATPase in hydrogen peroxide-induced activation of the Src/ERK pathway in LLC-PK1 cells

We have shown that Na/K-ATPase interacts with Src. Here, we test the role of this interaction in H(2)O(2)-induced activation of Src and ERK. We found that exposure of LLC-PK1 cells to H(2)O(2) generated by the addition of glucose oxidase into the culture medium activated Src and ERK1/2. It also caus...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Wang, Yu, Ye, Qiqi, Liu, Changxuan, Xie, Jeffrey X., Yan, Yanling, Lai, Fangfang, Duan, Qiming, Li, Xiaomei, Tian, Jiang, Xie, Zijian
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779055/
https://ncbi.nlm.nih.gov/pubmed/24703895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.036
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