Identification of a Mutant α1 Na/K-ATPase That Pumps but Is Defective in Signal Transduction

The α1 Na/K-ATPase possesses both pumping and signaling functions. However, it has not been possible to study these functions independently in live cells. We have identified a 20-amino acid peptide (Ser-415 to Gln-434) (NaKtide) from the nucleotide binding domain of α1 Na/K-ATPase that binds and inh...

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Библиографические подробности
Главные авторы: Lai, Fangfang, Madan, Namrata, Ye, Qiqi, Duan, Qiming, Li, Zhichuan, Wang, Shaomeng, Si, Shuyi, Xie, Zijian
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650368/
https://ncbi.nlm.nih.gov/pubmed/23532853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467381
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