Barcode sequencing identifies resistant mechanisms to epidermal growth factor receptor inhibitors in circulating tumor DNA of lung cancer patients

Most patients with epidermal growth factor receptor (EGFR) mutation‐positive non‐small cell lung cancer (NSCLC) will inevitably develop acquired resistance induced by treatment with EGFR tyrosine kinase inhibitors (EGFR‐TKI). The mechanisms of resistance to EGFR‐TKI are multifactorial, and the detec...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Kitazono, Satoru, Sakai, Kazuko, Yanagitani, Noriko, Ariyasu, Ryo, Yoshizawa, Takahiro, Dotsu, Yosuke, Koyama, Junji, Saiki, Masafumi, Sonoda, Tomoaki, Nishikawa, Shingo, Uchibori, Ken, Horiike, Atsushi, Nishio, Kazuto, Nishio, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778626/
https://ncbi.nlm.nih.gov/pubmed/31361375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14153
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