EGFR T790M mutation after chemotherapy for small cell lung cancer transformation of EGFR-positive non-small cell lung cancer

In non-small cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation, 50%–65% of cases acquire resistance after treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) because of an EGFR T790M point mutation and 3%–14% of these cases transformed to small cell lung cancer...

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Detalhes bibliográficos
Publicado no:Respir Med Case Rep
Main Authors: Sonoda, Tomoaki, Nishikawa, Shingo, Sakakibara, Rie, Saiki, Masafumi, Ariyasu, Ryo, Koyama, Junji, Kitazono, Satoru, Yanagitani, Noriko, Horiike, Atsushi, Ohyanagi, Fumiyoshi, Ninomiya, Hironori, Ishikawa, Yuichi, Nishio, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010587/
https://ncbi.nlm.nih.gov/pubmed/29977749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmcr.2018.03.009
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