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Modular synthesis of α-fluorinated arylmethanes via desulfonylative cross-coupling

α-Fluoromethylarenes are common substructures in pharmaceuticals and agrochemicals, with the introduction of fluorine often resulting in improved biological activity and stability. Despite recent progress, synthetic routes to α-fluorinated diarylmethanes are still rare. Herein we describe the Pd-cat...

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Vydáno v:Nat Commun
Hlavní autoři: Nambo, Masakazu, Yim, Jacky C.-H., Freitas, Luiza B. O., Tahara, Yasuyo, Ariki, Zachary T., Maekawa, Yuuki, Yokogawa, Daisuke, Crudden, Cathleen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778098/
https://ncbi.nlm.nih.gov/pubmed/31586048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11758-w
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