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MITF controls the TCA cycle to modulate the melanoma hypoxia response

In response to the dynamic intra‐tumor microenvironment, melanoma cells adopt distinct phenotypic states associated with differential expression of the microphthalmia‐associated transcription factor (MITF). The response to hypoxia is driven by hypoxia‐inducible transcription factors (HIFs) that repr...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Louphrasitthiphol, Pakavarin, Ledaki, Ioanna, Chauhan, Jagat, Falletta, Paola, Siddaway, Robert, Buffa, Francesca M., Mole, David R., Soga, Tomoyoshi, Goding, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777998/
https://ncbi.nlm.nih.gov/pubmed/31207090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12802
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