Fibulin-1c regulates transforming growth factor–β activation in pulmonary tissue fibrosis

Tissue remodeling/fibrosis is a major feature of all fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). It is underpinned by accumulating extracellular matrix (ECM) proteins. Fibulin-1c (Fbln1c) is a matricellular ECM protein associated with lung fibrosis in both humans and mice and s...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Liu, Gang, Cooley, Marion A., Jarnicki, Andrew G., Borghuis, Theo, Nair, Prema M., Tjin, Gavin, Hsu, Alan C., Haw, Tatt Jhong, Fricker, Michael, Harrison, Celeste L., Jones, Bernadette, Hansbro, Nicole G., Wark, Peter A., Horvat, Jay C., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777837/
https://ncbi.nlm.nih.gov/pubmed/31343988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124529
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