Self-reactive B cells in the GALT are actively curtailed to prevent gut inflammation

Immune homeostasis in the gut-associated lymphoid tissues (GALT) is critical to prevent the development of inadvertent pathologies. B cells, as the producers of antibodies and cytokines, play an important role in maintaining the GALT homeostasis. However, the mechanism by which B cells specifically...

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Pubblicato in:JCI Insight
Autori principali: Shukla, Ashima, Chen, Cindi, Jellusova, Julia, Leung, Charlotte R., Kao, Elaine, Bhat, Numana, Lin, Wai W., Apgar, John R., Rickert, Robert C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777813/
https://ncbi.nlm.nih.gov/pubmed/31335327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130621
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