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GSK3 is a metabolic checkpoint regulator in B cells

B cells predominate in a quiescent state until antigen is encountered, which results in rapid growth, proliferation and differentiation. These distinct cell states are likely accompanied by differing metabolic needs, yet little is known about the metabolic control of B cell fate. Here we show that g...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Jellusova, Julia, Cato, Matthew H., Apgar, John R., Ramezani-Rad, Parham, Leung, Charlotte, Chen, Cindi, Richardson, Adam D., Conner, Elaine M., Benschop, Robert J., Woodgett, James R., Rickert, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310963/
https://ncbi.nlm.nih.gov/pubmed/28114292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3664
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