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Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

Pancreatic ductal adenocarcinoma (PDA) is a major cause of cancer-related death, with limited therapeutic options available. This highlights the need for improved understanding of the biology of PDA progression, a highly complex and dynamic process, featuring changes in cancer cells and stromal cell...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hosein, Abdel Nasser, Huang, Huocong, Wang, Zhaoning, Parmar, Kamalpreet, Du, Wenting, Huang, Jonathan, Maitra, Anirban, Olson, Eric, Verma, Udit, Brekken, Rolf A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777805/
https://ncbi.nlm.nih.gov/pubmed/31335328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129212
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