Hypoxia-Inducible Factor-1α (HIF-1α) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13)

BACKGROUND: Hypoxia promotes cancer progression. Hypoxia-inducible factor-1α (HIF-1α) has been reported to enhance tumor invasion and metastasis via activating downstream genes, such as matrix metalloproteinases (MMPs). The purpose of this study was to explore the probable roles of HIF-1α and MMP13...

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Vydáno v:Med Sci Monit
Hlavní autoři: Zhang, Hui, Yang, Qingju, Lian, Xuanye, Jiang, Ping, Cui, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777377/
https://ncbi.nlm.nih.gov/pubmed/31587013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.916886
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