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Hypoxia-Inducible Factor-1α (HIF-1α) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13)

BACKGROUND: Hypoxia promotes cancer progression. Hypoxia-inducible factor-1α (HIF-1α) has been reported to enhance tumor invasion and metastasis via activating downstream genes, such as matrix metalloproteinases (MMPs). The purpose of this study was to explore the probable roles of HIF-1α and MMP13...

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Publicat a:Med Sci Monit
Autors principals: Zhang, Hui, Yang, Qingju, Lian, Xuanye, Jiang, Ping, Cui, Jing
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777377/
https://ncbi.nlm.nih.gov/pubmed/31587013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.916886
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