Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer

IMPORTANCE: Radiation therapy for breast cancer is associated with increased risk of a second primary contralateral breast cancer, but the genetic factors modifying this association are not well understood. OBJECTIVE: To determine whether a genetic risk score comprising single nucleotide polymorphis...

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Detalhes bibliográficos
Publicado no:JAMA Netw Open
Main Authors: Watt, Gordon P., Reiner, Anne S., Smith, Susan A., Stram, Daniel O., Capanu, Marinela, Malone, Kathleen E., Lynch, Charles F., John, Esther M., Knight, Julia A., Mellemkjær, Lene, Bernstein, Leslie, Brooks, Jennifer D., Woods, Meghan, Liang, Xiaolin, Haile, Robert W., Riaz, Nadeem, Conti, David V., Robson, Mark, Duggan, David, Boice, John D., Shore, Roy E., Tischkowitz, Marc, Orlow, Irene, Thomas, Duncan C., Concannon, Patrick, Bernstein, Jonine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777239/
https://ncbi.nlm.nih.gov/pubmed/31560388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.12259
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