Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer

IMPORTANCE: Radiation therapy for breast cancer is associated with increased risk of a second primary contralateral breast cancer, but the genetic factors modifying this association are not well understood. OBJECTIVE: To determine whether a genetic risk score comprising single nucleotide polymorphis...

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Опубликовано в: :JAMA Netw Open
Главные авторы: Watt, Gordon P., Reiner, Anne S., Smith, Susan A., Stram, Daniel O., Capanu, Marinela, Malone, Kathleen E., Lynch, Charles F., John, Esther M., Knight, Julia A., Mellemkjær, Lene, Bernstein, Leslie, Brooks, Jennifer D., Woods, Meghan, Liang, Xiaolin, Haile, Robert W., Riaz, Nadeem, Conti, David V., Robson, Mark, Duggan, David, Boice, John D., Shore, Roy E., Tischkowitz, Marc, Orlow, Irene, Thomas, Duncan C., Concannon, Patrick, Bernstein, Jonine L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Medical Association 2019
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777239/
https://ncbi.nlm.nih.gov/pubmed/31560388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.12259
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