The ubiquitin‐conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage

The autophagic clearance of damaged lysosomes by lysophagy involves extensive modification of the organelle with ubiquitin, but the underlying ubiquitination machinery is still poorly characterized. Here, we use an siRNA screening approach and identify human UBE2QL1 as a major regulator of lysosomal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Koerver, Lisa, Papadopoulos, Chrisovalantis, Liu, Bin, Kravic, Bojana, Rota, Giulia, Brecht, Lukas, Veenendaal, Tineke, Polajnar, Mira, Bluemke, Anika, Ehrmann, Michael, Klumperman, Judith, Jäättelä, Marja, Behrends, Christian, Meyer, Hemmo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776906/
https://ncbi.nlm.nih.gov/pubmed/31432621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados