Delivery of the autofluorescent protein R-phycoerythrin by calcium phosphate nanoparticles into four different eukaryotic cell lines (HeLa, HEK293T, MG-63, MC3T3): Highly efficient, but leading to endolysosomal proteolysis in HeLa and MC3T3 cells

Nanoparticles can be used as carriers to transport biomolecules like proteins and synthetic molecules across the cell membrane because many molecules are not able to cross the cell membrane on their own. The uptake of nanoparticles together with their cargo typically occurs via endocytosis, raising...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kopp, Mathis, Rotan, Olga, Papadopoulos, Chrisovalantis, Schulze, Nina, Meyer, Hemmo, Epple, Matthias
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460861/
https://ncbi.nlm.nih.gov/pubmed/28586345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178260
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