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Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling

Despite recently uncovered connections between autophagy and the endocytic pathway, the role of autophagy in regulating endosomal function remains incompletely understood. Here, we find that the ablation of autophagy‐essential players disrupts EGF‐induced endocytic trafficking of EGFR. Cells lacking...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Fraser, Jane, Simpson, Joanne, Fontana, Rosa, Kishi‐Itakura, Chieko, Ktistakis, Nicholas T, Gammoh, Noor
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776898/
https://ncbi.nlm.nih.gov/pubmed/31448519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947734
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