Extracellular IL-37 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the PI3K/AKT signaling pathway

Interleukin (IL)-37, a pivotal anti-inflammatory cytokine and a fundamental inhibitor of innate immunity, has recently been shown to be abnormally expressed in several autoimmune-related orthopedic diseases, including rheumatoid arthritis, ankylosing spondylitis, and osteoporosis. However, the role...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ye, Chenyi, Zhang, Wei, Hang, Kai, Chen, Mo, Hou, Weiduo, Chen, Jianzhong, Chen, Xi, Chen, Erman, Tang, Lan, Lu, Jinwei, Ding, Qianhai, Jiang, Guangyao, Hong, Baojian, He, Rongxin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776644/
https://ncbi.nlm.nih.gov/pubmed/31582734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1904-7
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