Hyperpolarized Pyruvate MR Spectroscopy Depicts Glycolytic Inhibition in a Mouse Model of Glioma

BACKGROUND: A generation of therapies targeting tumor metabolism is becoming available for treating glioma. Hyperpolarized MRI is uniquely suited to directly measure the metabolic effects of these emerging treatments. PURPOSE: To explore the feasibility of the use of hyperpolarized [1–carbon 13 {(13...

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Bibliographic Details
Published in:Radiology
Main Authors: Michel, Keith A., Zieliński, Rafal, Walker, Christopher M., Le Roux, Lucia, Priebe, Waldemar, Bankson, James A., Schellingerhout, Dawid
Format: Artigo
Language:Inglês
Published: Radiological Society of North America 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776231/
https://ncbi.nlm.nih.gov/pubmed/31385757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2019182919
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