Influence of Parameter Accuracy on Pharmacokinetic Analysis of Hyperpolarized Pyruvate

PURPOSE: To explore the effects of noise and error on kinetic analyses of tumor metabolism using hyperpolarized [1-(13)C] pyruvate. METHODS: Numerical simulations were performed to systematically investigate the effects of noise, the number of unknowns, and error in kinetic parameter estimates on ki...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Magn Reson Med
Main Authors: Sun, Chang-yu, Walker, Christopher M., Michel, Keith A., Venkatesan, Aradhana M., Lai, Stephen Y., Bankson, James A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843516/
https://ncbi.nlm.nih.gov/pubmed/29090487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26992
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