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Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease
BACKGROUND: Prodromal Alzheimer’s disease offers an opportunity to test the effect of drugs that modify the deposition of amyloid in the brain before the onset of dementia. Verubecestat is an orally administered β-site amyloid precursor protein-cleaving enzyme 1 (BACE-1) inhibitor that blocks produc...
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| Pubblicato in: | N Engl J Med |
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| Autori principali: | , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6776078/ https://ncbi.nlm.nih.gov/pubmed/30970186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1812840 |
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