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Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension

Inflammation and vascular smooth muscle cell (VSMC) phenotypic switching are causally linked to pulmonary arterial hypertension (PAH) pathogenesis. Carbonic anhydrase inhibition induces mild metabolic acidosis and exerts protective effects in hypoxic pulmonary hypertension. Carbonic anhydrases and m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Hudalla, Hannes, Michael, Zoe, Christodoulou, Nicolas, Willis, Gareth R., Fernandez-Gonzalez, Angeles, Filatava, Evgenia J., Dieffenbach, Paul, Fredenburgh, Laura E., Stearman, Robert S., Geraci, Mark W., Kourembanas, Stella, Christou, Helen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775956/
https://ncbi.nlm.nih.gov/pubmed/30951642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0232OC
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