In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model

Ras homolog family member A (RHOA) mutations are driver genes in diffuse-type gastric cancers (DGCs), and we previously revealed that RHOA mutations contribute to cancer cell survival and cell migration through their dominant negative effect on Rho-associated kinase (ROCK) signaling in vitro. Howeve...

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Pubblicato in:Oncol Rep
Autori principali: Nishizawa, Takashi, Nakano, Kiyotaka, Fujii, Etsuko, Komura, Daisuke, Kuroiwa, Yoshie, Ishimaru, Chisako, Monnai, Makoto, Aburatani, Hiroyuki, Ishikawa, Shumpei, Suzuki, Masami
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775816/
https://ncbi.nlm.nih.gov/pubmed/31485674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7300
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