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Tumor clonal status predicts clinical outcomes of lung adenocarcinoma with EGFR-TKI sensitizing mutation

Objectives: Intratumoral heterogeneity is one of major causes of resistance to therapeutic. Here, we evaluated clonal status, which may reflect intratumoral heterogeneity, in lung adenocarcinoma with EGFR-TKI sensitizing mutation (mEGFR) and its clinical implications. Materials and Methods: Customiz...

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Kim, Eun Young, Lee, Sang Hoon, Kim, Arum, Kim, Taehee, Chang, Yoon Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775702/
https://ncbi.nlm.nih.gov/pubmed/31632498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.32897
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