Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke

Triggering receptor expressed on myeloid cells-2 (TREM2) is an innate immune receptor that promotes phagocytosis by myeloid cells such as microglia and macrophages. We previously showed that TREM2 deficiency worsened outcomes from experimental stroke and impeded phagocytosis. However, myeloid cells...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Kurisu, Kota, Zheng, Zhen, Kim, Jong Youl, Shi, Jian, Kanoke, Atsushi, Liu, Jialing, Hsieh, Christine L, Yenari, Midori A
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775587/
https://ncbi.nlm.nih.gov/pubmed/30523715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18817282
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