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Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke

Triggering receptor expressed on myeloid cells-2 (TREM2) is an innate immune receptor that promotes phagocytosis by myeloid cells such as microglia and macrophages. We previously showed that TREM2 deficiency worsened outcomes from experimental stroke and impeded phagocytosis. However, myeloid cells...

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Bibliografski detalji
Izdano u:J Cereb Blood Flow Metab
Glavni autori: Kurisu, Kota, Zheng, Zhen, Kim, Jong Youl, Shi, Jian, Kanoke, Atsushi, Liu, Jialing, Hsieh, Christine L, Yenari, Midori A
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775587/
https://ncbi.nlm.nih.gov/pubmed/30523715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18817282
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