A Single Nucleotide C3 Polymorphism Associates With Clinical Outcome After Lung Transplantation

Background: Development of chronic rejection is still a severe problem and causes high mortality rates after lung transplantation (LTx). Complement activation is important in the development of acute rejection (AR) and bronchiolitis obliterans syndrome, with C3 as a key complement factor. Methods: W...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Kardol-Hoefnagel, Tineke, Budding, Kevin, van de Graaf, Eduard A., van Setten, Jessica, van Rossum, Oliver A., Oudijk, Erik-Jan D., Otten, Henderikus G.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775212/
https://ncbi.nlm.nih.gov/pubmed/31616421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02245
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