The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation

Obstructive chronic lung allograft dysfunction (BOS) is the major limiting factor for lung transplantation (LTx) outcome. PTPN22 is described as the hallmark autoimmunity gene, and one specific single nucleotide polymorphism (SNP), rs2476601, is associated with multiple autoimmune diseases, impaired...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Budding, Kevin, van Setten, Jessica, van de Graaf, Eduard A., van Rossum, Oliver A., Kardol-Hoefnagel, Tineke, Kwakkel-van Erp, Johanna M., Oudijk, Erik-Jan D., Hack, C. Erik, Otten, Henderikus G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344400/
https://ncbi.nlm.nih.gov/pubmed/30705675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03105
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