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Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

In contrast to mammals, adult fish display a remarkable ability to fully regenerate central nervous system (CNS) axons, enabling functional recovery from CNS injury. Both fish and mammals normally undergo a developmental downregulation of axon growth activity as neurons mature. Fish are able to unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dhara, Sumona P., Rau, Andrea, Flister, Michael J., Recka, Nicole M., Laiosa, Michael D., Auer, Paul L., Udvadia, Ava J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775158/
https://ncbi.nlm.nih.gov/pubmed/31578350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50485-6
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