Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle

Nesprins, nuclear envelope spectrin-repeat proteins encoded by the SYNE1 and SYNE2 genes, are involved in localization of nuclei. The short isoform, nesprin-1-alpha2, is required for relocation of the microtubule organizer function from centromeres to the nuclear rim during myogenesis. Using specifi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Holt, Ian, Fuller, Heidi R., Lam, Le Thanh, Sewry, Caroline A., Shirran, Sally L., Zhang, Qiuping, Shanahan, Catherine M., Morris, Glenn E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775114/
https://ncbi.nlm.nih.gov/pubmed/31578382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50728-6
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