Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy

Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules. The natural compound nordihydroguaiaretic acid (NDGA) robustly increases lifespan in flies and...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Tezil, Tugsan, Chamoli, Manish, Ng, Che-Ping, Simon, Roman P., Butler, Victoria J., Jung, Manfred, Andersen, Julie, Kao, Aimee W., Verdin, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775102/
https://ncbi.nlm.nih.gov/pubmed/31602311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-019-0037-7
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