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The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity
In eukaryotes, pyridoxal kinase (PDXK) acts in vitamin B(6) salvage pathway to produce pyridoxal 5′-phosphate (PLP), the active form of the vitamin, which is implicated in numerous crucial metabolic reactions. In Drosophila, mutations in the dPdxk gene cause chromosome aberrations (CABs) and increas...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6775053/ https://ncbi.nlm.nih.gov/pubmed/31578392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50673-4 |
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