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Decoding tumor mutation burden and driver mutations in early stage lung adenocarcinoma using CT‐based radiomics signature

BACKGROUND: Tumor mutation burden (TMB) is an important determinant and biomarker for response of targeted therapy and prognosis in patients with lung cancer. The present study aimed to determine whether radiomics signature could non‐invasively predict the TMB status and driver mutations in patients...

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Vydáno v:Thorac Cancer
Hlavní autoři: Wang, Xiaoxiao, Kong, Cheng, Xu, Weizhang, Yang, Sheng, Shi, Dan, Zhang, Jingyuan, Du, Mulong, Wang, Siwei, Bai, Yongkang, Zhang, Te, Chen, Zeng, Ma, Zhifei, Wang, Jie, Dong, Gaochao, Sun, Mengting, Yin, Rong, Chen, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Australia, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775017/
https://ncbi.nlm.nih.gov/pubmed/31414580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13163
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