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Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal malignancy of the biliary tract. Analysis of somatic mutational profiling can reveal new prognostic markers and actionable treatment targets. In this study, we explored the utility of genomic mutation signature and tumor mutation...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Zhang, Rui, Li, Qi, Fu, Jialu, Jin, Zhechuan, Su, Jingbo, Zhang, Jian, Chen, Chen, Geng, Zhimin, Zhang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860034/
https://ncbi.nlm.nih.gov/pubmed/33535978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07788-7
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