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Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements

BACKGROUND: Understanding the molecular mechanisms in perturbation of the metabolome following ischaemia and reperfusion is critical in developing novel therapeutic strategies to prevent the sequelae of post-injury shock. While the metabolic substrates fueling these alterations have been defined, th...

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Bibliographic Details
Published in:Blood Transfus
Main Authors: Clendenen, Nathan, Nunns, Geoffrey R., Moore, Ernest E., Gonzalez, Eduardo, Chapman, Michael, Reisz, Julie A., Peltz, Erik, Fragoso, Miguel, Nemkov, Travis, Wither, Matthew J., Sauaia, Angela, Silliman, Christopher C., Hansen, Kirk, Banerjee, Anirban, D‘Alessandro, Angelo, Moore, Hunter B.
Format: Artigo
Language:Inglês
Published: Edizioni SIMTI - SIMTI Servizi Srl 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774928/
https://ncbi.nlm.nih.gov/pubmed/30747701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2018.0188-18
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