Plasma first resuscitation reduces lactate acidosis, enhances redox homeostasis, amino acid and purine catabolism in a rat model of profound hemorrhagic shock

The use of aggressive crystalloid resuscitation to treat hypoxemia, hypovolemia and nutrient deprivation promoted by massive blood loss may lead to the development of the blood vicious cycle of acidosis, hypothermia, and coagulopathy and, utterly, death. Metabolic acidosis is one of the many metabol...

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Vydáno v:Shock
Hlavní autoři: D’Alessandro, Angelo, Moore, Hunter B, Moore, Ernest E, Wither, Matthew J., Nemkov, Travis, Morton, Alexander P, Gonzalez, Eduardo, Chapman, Michael P, Fragoso, Miguel, Slaughter, Anne, Sauaia, Angela, Silliman, Christopher C, Hansen, Kirk C, Banerjee, Anirban
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949141/
https://ncbi.nlm.nih.gov/pubmed/26863033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000588
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