Shock-Induced Systemic Hyperfibrinolysis is Attenuated by Plasma First Resuscitation

BACKGROUND: We developed a hemorrhagic shock animal model to replicate an urban prehospital setting where resuscitation fluids are limited to assess the effect of saline versus plasma in coagulopathic patients. An in vitro model of whole blood dilution with saline exacerbated tPA mediated fibrinolys...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Moore, Hunter B., Moore, Ernest E., Morton, Alexander P., Gonzalez, Eduardo, Fragoso, Miguel, Chapman, Michael P., Dzieciatkowska, Monika, Hansen, Kirk C., Banerjee, Anirban, Sauaia, Angela, Silliman, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686159/
https://ncbi.nlm.nih.gov/pubmed/26680132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000792
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