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Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival

PURPOSE: Metabolomics is a discovery tool for novel associations of metabolites with disease. Here, we interrogated the metabolome of human breast tumors to describe metabolites whose accumulation affects tumor biology. EXPERIMENTAL DESIGN: We applied large-scale metabolomics followed by absolute qu...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Tang, Wei, Putluri, Vasanta, Ambati, Chandrashekar R., Dorsey, Tiffany H., Putluri, Nagireddy, Ambs, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774910/
https://ncbi.nlm.nih.gov/pubmed/31296531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0094
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