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Conformational changes in HIV-1 reverse transcriptase that facilitate its maturation
HIV-1 reverse transcriptase (RT) is translated as part of the Gag-Pol polyprotein that is proteolytically processed by HIV-1 protease (PR) to finally become a mature heterodimer, composed of a p66 and a p66-derived 51 kDa subunit, p51. Our prior work suggested that tRNA(Lys3) binding to p66/p66 intr...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6774901/ https://ncbi.nlm.nih.gov/pubmed/31471129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.08.004 |
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