Association between zidovudine-containing antiretroviral therapy exposure in utero and leukocyte telomere length at birth

OBJECTIVES: Zidovudine (ZDV) is a nucleoside reverse transcriptase inhibitor that could cause telomere shortening through inhibition of telomerase. We examined the association between in utero exposure to ZDV and telomere length (TL) at birth in HIV-exposed uninfected (HEU) newborns. METHODS: We sel...

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Veröffentlicht in:AIDS
Hauptverfasser: WANG, Youjin, BRUMMEL, Sean S., BEILSTEIN-WEDEL, Erin, DAGNALL, Casey L., HAZRA, Rohan, KACANEK, Deborah, CHADWICK, Ellen G., MARSIT, Carmen J., CHANOCK, Stephen J., SAVAGE, Sharon A., POIRIER, Miriam C., MACHIELA, Mitchell J., ENGELS, Eric A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774838/
https://ncbi.nlm.nih.gov/pubmed/31335808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002317
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